Endocrine Abstracts

Introduction: Pregnancy is a stress test on maternal thyroid and pregnant women may be more susceptible to thyroid dysfunction. Consequences of this may be harmful for the mother and fetus. Smoking has been associated with alterations in thyroid hormone concentrations, but little knowledge exists on this association in pregnant women.Subjects and methods: The study population is large, prospective population-based Northern Finland Birth Cohort 1986 (n...

Introduction: Hyperandrogenaemia in adolescence is associated with hirsutism, acne and menstrual irregularity and is considered as an important risk for polycystic ovary syndrome and subsequent risk of cardiovascular disease and type 2 diabetes. The aim of this study was to establish if self-reported oligo/amenorrhea were associated with hyperandrogenemia and metabolic disturbances in adolescence.Subjects and methods: A cross sectional study using postal...

Introduction: Foetus is dependent on maternal thyroid hormone production during the first trimester. Thus, maternal thyroid dysfunction and thyroid antibodies may affect thyroid function of the offspring.Subjects and methods: We studied a subcohort (n=2000 mother–child-pairs) from a prospective population-based Northern Finland Birth Cohort 1986 (singleton births, total n=9247) covering data throughout pregnancy, childhood and adolesce...